海外文献
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Subretinal Fibrosis and Uveitis Syndrome
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Type 1 Nonexudative Macular Neovascularization: 10-Year Follow-Up with En Face OCT
An 88-year-old patient with nonexudative type 1 macular neovascularization (MNV) and a final visual acuity of 20/30 in the right eye and 20/25 in the left eye was followed for 10 years with multimodal
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At a glance
Long-term outcomes of and a risk score model for moderate-risk to high-risk penetrating keratoplasty (see page 981) This study developed a risk score for moderate- to high-risk penetrating keratoplast
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Techniques for MSICS for Hard Cataracts - Review of Ophthalmology
Techniques for MSICS for Hard Cataracts Review of Ophthalmology
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Sutureless Conjunctiva-Sparing Müllerectomy
← Older revision Revision as of 23:55, September 10, 2026 (8 intermediate revisions by the same user not shown) Line 10: Line 10: Posterior approach ptosis surgery has evolved through successive modif
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Myopic Traction Maculopathy: consensus from the Myopia Society for a new nomenclature
To establish a standardized, clinically relevant nomenclature for myopic traction maculopathy (MTM) that prioritizes lesions based on visual impact and potential prognostic significance.
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Corneal confocal microscopy as a paraclinical test in neurodegenerative disease: a scoping review
Corneal confocal microscopy (CCM) is a non-invasive imaging technique that enables quantification of the corneal sub-basal nerve plexus and has emerged as a potential surrogate biomarker for periphera
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All About Refractive Lens Exchange - Review of Ophthalmology
All About Refractive Lens Exchange Review of Ophthalmology
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Clinical Trials in Oculoplastics
← Older revision Revision as of 20:16, September 10, 2026 Line 1: Line 1: {{Article {{Article |Authors= Andrew.G.Lee, Bruce.B.Becker, Jainam.Shah, Gagandeep Mudhar, Jason.Zheng, Sachin.Pathuri |Author
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Prophylactic Retinopexy in Fellow Eyes After Contralateral Retinal Detachment: A Systematic Review and Meta-analysis
To evaluate whether prophylactic retinopexy reduces the risk of retinal detachment (RD) in fellow eyes after contralateral RD, and to explore whether effect estimates differ by lesion subtypes.
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Long-term outcomes of and a risk score model for moderate-risk to high-risk penetrating keratoplasty
Background/Aims To develop a risk score for moderate-risk to high-risk penetrating keratoplasty (PK) based on various risk factors and use it to stratify grafts. Methods We collected data on clinical
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Study: Anti-VEGF Access Varies in Medicare Plans - Review of Ophthalmology
Study: Anti-VEGF Access Varies in Medicare Plans Review of Ophthalmology
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Dysplastic Nevus Syndrome
← Older revision Revision as of 17:07, September 10, 2026 Line 8: Line 8: }} }} |Reviewer=Christina.H.Choe |Reviewer=Christina.H.Choe |Date reviewed= March 1 , 2026 |Date reviewed= September 10 , 2026
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Two-Year Experience with Intravitreal Pegcetacoplan for the Treatment of Geographic Atrophy in Clinical Practice
Geographic atrophy (GA) is the late form of non-exudative (dry) age-related macular degeneration (AMD), and its relentless progression leads to irreversible vision loss.1,2 In 2023, two complement inh
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An Optociliary Shunt Vessel in Optic Nerve Sheath Meningioma
A 49-year-old woman presented with a 10-month history of blurred vision in her left eye. Best-corrected visual acuity was 20/20 in the right eye and 20/66 in the left eye. Fundus examination showed fl
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Mitomycin C-based angio-regression for corneal neovascularisation: outcomes with intravascular (MICE), intrastromal (MIST) and combined delivery routes
Background Corneal neovascularisation (NV) is a refractory condition associated with lipid deposition, scarring and vision loss. Mitomycin C (MMC) intravascular chemoembolisation (MICE) has shown earl
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Early Detection in Corneal Disease - Review of Ophthalmology
Early Detection in Corneal Disease Review of Ophthalmology
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Clinical Trials in Oculoplastics
← Older revision Revision as of 16:46, September 10, 2026 Line 1: Line 1: {{Article {{Article |Authors=Jainam.Shah, Gagandeep Mudhar, Jason.Zheng, Sachin.Pathuri , Andrew.G.Lee, Bruce.B.Becker |Author
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Comment on “Noncombustible nicotine or tobacco product use after smoking cessation and major vision-impairing diseases: a nationwide cohort study”
We read with interest the nationwide cohort study by Cheon et al. examining noncombustible nicotine or tobacco product use after smoking cessation and the risk of major vision-impairing eye diseases [
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Clinical features, retinal detachment (RD) rates, and RD prophylaxis in patients with genetically confirmed Knobloch Syndrome, a U.S.-based multi-center study
Knobloch syndrome is a rare autosomal recessive condition characterized by lack of functional collagen type XVIII (COL18A1), occipital defects, high myopia, and vitreoretinal degeneration. Clinical fe
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Malignant melanocytic lesions in clinically suspected pterygium
Aims To determine the prevalence and clinicopathological features of malignant melanocytic lesions in specimens clinically diagnosed as pterygia. Methods This retrospective study analysed all conjunct
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August 2026 Wills Eye Resident Case Series - Review of Ophthalmology
August 2026 Wills Eye Resident Case Series Review of Ophthalmology
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Nonspecific Orbital Inflammation (Idiopathic Orbital Inflammation, Orbital Inflammatory Syndrome, Orbital Pseudotumor)
← Older revision Revision as of 11:56, September 10, 2026 Line 1: Line 1: {{Article {{Article |Authors=Anupama Chundury, Gabriella M. Espinoza, Rao V. Chundury |Authors=Anupama Chundury, Gabriella M.
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Cystoid Macular Edema After Cultured Human Corneal Endothelial Cell Injection: Frequency, Associated Factors, and Visual Outcomes
To evaluate the frequency, timing, factors associated with, and visual impact of cystoid macular edema (CME) detected after cultured human corneal endothelial cell (cHCEC) injection therapy.
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Longitudinal Changes in Inner Retinal Layers in Treatment-Naïve Neovascular AMD During Intravitreal Anti-VEGF Therapy
To investigate longitudinal changes in retinal nerve fiber layer (RNFL) and ganglion cell- inner plexiform layer (GC-IPL) thickness in treatment-naïve neovascular age-related macular degeneration (nAM
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Nationwide age-, sex-, cause-specific burden of blindness and vision impairment in China
Background Despite over 90% of vision impairment (VI) being preventable, in China, a routine screening programme is currently unavailable in primary healthcare. Robust epidemiological evidence is need
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Taking Out a Light-Adjustable Lens - Review of Ophthalmology
Taking Out a Light-Adjustable Lens Review of Ophthalmology
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Cerebro-Oculo-Facial-Skeletal Syndrome
← Older revision Revision as of 10:09, September 10, 2026 (One intermediate revision by the same user not shown) Line 8: Line 8: }} }} |Reviewer=Natalie.Homer |Reviewer=Natalie.Homer |Date reviewed= M
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Reply to Comment on Temporal Patterns of Posterior Segment Imaging Findings and Laboratory Correlates in Ocular Syphilis
We thank Singh and colleagues for their constructive analysis of our study. Their comments prompted us to return to the eye-level data and reassess our findings using modality- and block-specific deno
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GLP1-RA Use and Risk of Non-arteritic Anterior Ischemic Optic Neuropathy in Patients with Type 2 Diabetes
Concerns have been raised regarding the increased risk of non-arteritic ischemic optic neuropathy (NAION) associated with the use of glucagon-like peptide 1 receptor agonist (GLP-1 RA). However, findi
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Biomarker changes of choroidal architecture preceding myopia onset in Chinese school children: a 3-year prospective cohort study
Background/aims To characterise the temporal dynamics of choroidal changes relative to myopia onset and determine their associations with myopia onset in school children. Methods The 3-year prospectiv
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Study Examines Reasons for IOL Explantations - Review of Ophthalmology
Study Examines Reasons for IOL Explantations Review of Ophthalmology
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Carotid Cavernous Fistula
← Older revision Revision as of 10:03, September 10, 2026 Line 8: Line 8: }} }} |Reviewer=Natalie.Homer |Reviewer=Natalie.Homer |Date reviewed= March 12 , 2026 |Date reviewed= September 10 , 2026 |Art
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Stability, Safety, and Efficacy of WaveLight Plus InnovEyes Ray-Tracing-Guided LASIK in Myopia and Myopic Astigmatism: A One-Year Prospective Study
The number of people with short-sightedness (myopia) has increased across the world․ The number of people with myopia was estimated to be 22.9% in 2000 and 34.0% in 2020․By 2050‚ close to half of the
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Evidence and Consensus Based Imaging Guidelines in Ocular Toxoplasmosis. Multimodal imaging in Uveitis (MUV) Taskforce Report 14
To develop imaging and consensus-based guidelines for the application of multimodal imaging in ocular toxoplasmosis (OT).
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Amblyopia and adult health: a comprehensive analysis of long-term systemic, sensory and mental health comorbidities in a national cohort
Aims To evaluate the adult health consequences of amblyopia, including sensory deficits, mental health, physical activity and cardiovascular health. Methods A cross-sectional study using data from the
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Systemic Medications And Angle Closure - Review of Ophthalmology
Systemic Medications And Angle Closure Review of Ophthalmology
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Clinical Trials in Oculoplastics
Results ← Older revision Revision as of 05:19, September 10, 2026 (One intermediate revision by the same user not shown) Line 14: Line 14: This article reviews the evolving landscape of clinical trial
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Three-year efficacy and safety of repeated low-level red-light therapy for myopia control: a multicentre real-world study
Background To evaluate the efficacy and safety of repeated low-level red-light (RLRL) therapy for controlling myopia progression over 3 years in real-world settings. Methods This multicentre cohort st
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Novel Complications Following Cataract Surgery - Review of Ophthalmology
Novel Complications Following Cataract Surgery Review of Ophthalmology
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Sutureless Conjunctiva-Sparing Müllerectomy
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Comment on “Temporal Patterns of Posterior Segment Imaging Findings and Laboratory Correlates in Ocular Syphilis”
We read with interest the article by Rhead and associates describing temporal patterns of posterior segment imaging findings and laboratory correlates in ocular syphilis.1 The authors conclude that im
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Aetiology, characteristics and workup of early onset high myopia
Background Early-onset high myopia (eoHM) associates with multiple ocular and systemic disorders. This study evaluates the repertoire and relative prevalence of these disorders in a tertiary care sett
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10 Pearls for Diabetic Vitrectomy - Review of Ophthalmology
10 Pearls for Diabetic Vitrectomy Review of Ophthalmology
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Benign Yellow Dot Maculopathy
Disease ← Older revision Revision as of 23:26, September 8, 2026 Line 14: Line 14: = Disease Entity = = Disease Entity = Benign Yellow Dot Maculopathy / Benign Yellow Dot Maculopathy == Disease == ==
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Reticular Pseudodrusen Subtypes and Their Interaction With Soft Drusen: Longitudinal Structure–Function Analysis
To evaluate longitudinal structure–function relationships of reticular pseudodrusen (RPD) subtypes and their interaction with soft drusen (SD) on retinal sensitivity (RS) in intermediate age-related m
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Re: Holz et al.: Adherence to intravitreal aflibercept in neovascular age-related macular degeneration: 24-month results from the ANDROMEDA Study (Ophthalmol. Retina. 2026;10:241-249)
Holz et al1 present the ANDROMEDA study, a prospective multicenter investigation evaluating adherence to intravitreal aflibercept therapy in patients with neovascular age-related macular degeneration
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Aqueous humour outflow improvement after excimer laser trabeculostomy
The purpose of the study was to investigate changes in aqueous humour outflow (AHO) after the Elios glaucoma procedure (excimer laser trabeculostomy, ELT) using sequential AHO angiography. AHO angiogr
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July 2026 Wills Eye Resident Case Series - Review of Ophthalmology
July 2026 Wills Eye Resident Case Series Review of Ophthalmology
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Robotic-Assisted Vitreoretinal Surgery
Surgical Therapy Show changes
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Reply to Comment on, "Glaucoma and Neurodegenerative Disease Risk: A 10-Year Assessment of Real-World Global Data"
Comment on, "Glaucoma and Neurodegenerative Disease Risk: A 10-Year Assessment of Real-World Global Data"
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SSGJ-601 versus Ranibizumab for Macular Edema Secondary to Branch Retinal Vein Occlusion: 52-Week Results from a Phase 3 Study
To evaluate the clinical efficacy, safety, and immunogenicity of biosimilar SSGJ-601 compared with ranibizumab in patients with macular edema secondary to branch retinal vein occlusion (BRVO).
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Optic nerve intraneural pressure trend under intraocular-intracranial pressure effects
The imbalance between intraocular pressure (IOP) and intracranial pressure (ICP) is a recognised contributor to optic nerve (ON) injury. Clinically, the translaminar pressure difference is often simpl
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OCT Imaging Pearls in AMD Management - Review of Ophthalmology
OCT Imaging Pearls in AMD Management Review of Ophthalmology
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Epidemic Keratoconjunctivitis
← Older revision Revision as of 18:56, September 8, 2026 (One intermediate revision by the same user not shown) Line 7: Line 7: |Date assigned=March 23, 2015 11:23:26 PM |Date assigned=March 23, 2015
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Comment on, “Glaucoma and Neurodegenerative Disease Risk: A 10-Year Assessment of Real-World Global Data”
We read with interest the study by Wong et al., which reports an observational association between glaucoma and subsequent neurodegenerative diagnoses, with associations varying by age at diagnosis an
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Retinal Detachment Reporting Following Topical Pilocarpine 1.25% for Presbyopia
Topical pilocarpine 1.25% ophthalmic solution (Vuity; AbbVie), approved by the U.S. Food and Drug Administration (FDA) in October 2021 for presbyopia, is the first pharmacologic miotic agent widely ma
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Association of high-pillow sleeping posture with intraocular pressure in patients with glaucoma
Background Intraocular pressure (IOP) exhibits significant fluctuations in response to changes in body posture. Postural modification may serve as a potential adjunctive strategy for IOP management in
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Navigating Macular Hole Surgery - Review of Ophthalmology
Navigating Macular Hole Surgery Review of Ophthalmology
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Branch Retinal Vein Occlusion
← Older revision Revision as of 13:53, September 8, 2026 (One intermediate revision by the same user not shown) Line 7: Line 7: }} }} |Reviewer=Jason.Hsu |Reviewer=Jason.Hsu |Date reviewed= February 1
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Cumulative Atopic Disease Burden and Keratoconus: Cross-Sectional and Longitudinal Associations in the All of Us Research Program
To evaluate the association between cumulative atopic disease burden and keratoconus (KC) in a large, diverse United States cohort.
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Evidence and Consensus Based Guidelines in Behçet Disease Uveitis. Multimodal imaging in Uveitis (MUV) Taskforce Report 18
To develop imaging and consensus-based guidelines for the application of multimodal imaging in the clinical diagnosis, monitoring and detection of complications in Behçet disease (BD) uveitis.
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Associations between obesity, metabolic syndrome and glaucoma in the National Institutes of Health 'All of Us research programme
Background/aims The literature surrounding the relationship between obesity and glaucoma is conflicting. The aim of this study was to examine associations between obesity, metabolic syndrome (MetS) an
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Pearls for Implanting the EVO+ ICL - Review of Ophthalmology
Pearls for Implanting the EVO+ ICL Review of Ophthalmology
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Visual Neglect
← Older revision Revision as of 10:49, September 8, 2026 Line 7: Line 7: }} }} |Reviewer=Sonali.Singh |Reviewer=Sonali.Singh |Date reviewed= March 10 , 2026 |Date reviewed= September 8 , 2026 |Article
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Real-World Applicability of Anti-VEGF Trial Criteria for Diabetic Macular Edema
To characterize the real-world eligibility based on systemic medical criteria of patients receiving anti-VEGF injections for DME, including potential rates of trial exclusion and associated patient de
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Late Recurrent Coats’ Disease: Clinical Characteristics and Treatment Outcome
To investigate the clinical characteristics and outcomes of late recurrent Coats’ disease after complete resolution.
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Incidence and treatment patterns of acute retinal necrosis: a nationwide population-based cohort study
Aims To quantify nationwide incidence and contemporary treatment patterns of acute retinal necrosis (ARN). Methods Retrospective cohort using Japan’s National Database of Health Insurance Claims and S
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How To Be Drop-free - Review of Ophthalmology
How To Be Drop-free Review of Ophthalmology
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Benign Yellow Dot Maculopathy
Disease Entity ← Older revision Revision as of 09:59, September 8, 2026 Line 14: Line 14: = Disease Entity = = Disease Entity = Benign Yellow Dot Maculopathy Benign Yellow Dot Maculopathy / == Disease
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Central obesity in women and high overall body fat in men are associated with higher odds of dry eye disease
To compare associations of BMI, total body fat percentage, and fat distribution with dry eye disease (DED) and assess metabolites mediation.
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The Manchester buckle study: 15-year outcomes and predictive factors for success in scleral buckling for primary rhegmatogenous retinal detachment
Aims To assess the long-term anatomical and visual outcomes of primary scleral buckle (SB) surgery for rhegmatogenous retinal detachment (RRD) and identify predictors of surgical and functional succes
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Retinopathy in Dyskeratosis Congenita and Related Telomere Biology Disorders: Short Telomere Associated Retinopathy (STAR)
Dyskeratosis congenita (DC) and related telomere biology disorders (TBD) are rare hereditary conditions caused by genetic impairments of telomere maintenance. We present the largest study to date desc
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Current Approaches for Vitreous Floater Treatment - Review of Ophthalmology
Current Approaches for Vitreous Floater Treatment Review of Ophthalmology
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Harlequin Syndrome/Harlequin Sign
← Older revision Revision as of 09:46, September 8, 2026 Line 8: Line 8: }} }} |Reviewer=Sonali.Singh |Reviewer=Sonali.Singh |Date reviewed= March 9 , 2026 |Date reviewed= September 8 , 2026 |Article
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USH2A-Associated Retinitis Pigmentosa in Koreans: Molecular Genetics and Clinical Characteristics
Retinitis pigmentosa (RP) is the most common form of inherited retinal degeneration, affecting approximately 1 in 4,000 individuals worldwide.1 The disease is characterized by progressive degeneration
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Optical coherence tomography angiography reveals microvascular changes and predicts visual outcomes after decompression surgery for pituitary adenoma
Background/aims To evaluate retinal microvascular changes using optical coherence tomography angiography (OCTA) and their prognostic value in patients undergoing transsphenoidal surgery for pituitary
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Toward Multimodal Conversational AI for Age-Related Macular Degeneration
To evaluate OcularChat, an age-related macular degeneration (AMD)-specific multimodal large language model for interpreting color fundus photographs.
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Considerations for Pediatric Refractive Surgery - Review of Ophthalmology
Considerations for Pediatric Refractive Surgery Review of Ophthalmology
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Robotic-Assisted Vitreoretinal Surgery
Surgical Therapy Show changes
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LYNX-1: A Phase 3 Study of 0.75% Phentolamine Ophthalmic Solution in Subjects with Dim Light Vision Disturbances
When the pupil dilates under mesopic conditions, peripheral light rays, previously blocked by the constricted iris, can enter the eye through the expanded entrance pupil. In eyes with optical aberrati
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Trauma-related eye removal is associated with increased psychiatric morbidity compared to other surgical indications: a retrospective cohort study
Background/aims To evaluate psychiatric outcomes following enucleation or evisceration (EE) and determine whether these outcomes differ by the underlying aetiology related to surgery, including trauma
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Choroidal Amyloid Angiopathy with Fireworks Pattern on Late-Frames Indocyanine Green Angiography
A 43-year-old man was referred for idiopathic central serous chorioretinopathy in his left eye with a visual acuity of 20/50. Five years earlier, he had undergone liver transplantation for hereditary
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Dysphotopsia Classification System Developed - Review of Ophthalmology
Dysphotopsia Classification System Developed Review of Ophthalmology
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Chromatopsia
← Older revision Revision as of 09:40, September 8, 2026 Line 8: Line 8: }} }} |Reviewer=Sonali.Singh |Reviewer=Sonali.Singh |Date reviewed= March 6 , 2026 |Date reviewed= September 8 , 2026 |Article
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Changing Trends in the Microbiological spectrum and clinical presentation of Postcataract Endophthalmitis over a 23-year period
Cataract surgery remains the most frequently performed ophthalmologic surgery worldwide. Despite technical advances, acute postoperative endophthalmitis, although rare, represents the most serious com
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Outcome reporting bias in ophthalmology clinical trials between 2014 and 2023
Background Outcome-reporting bias (ORB), characterised by selective outcome reporting, may exaggerate intervention efficacy and safety, compromising clinical guidelines and patient care. This cross-se
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Tetracycline-class Antibiotics for Proliferative Retinopathy Prevention: Still Too Many Unanswered Questions
The authors have no proprietary or commercial interest in any materials discussed in this article.
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The Rise of VR Perimetry - Review of Ophthalmology
The Rise of VR Perimetry Review of Ophthalmology
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Corneal Epithelial Defect
← Older revision Revision as of 17:21, September 7, 2026 Line 7: Line 7: }} }} |Reviewer=Maria.Bernal |Reviewer=Maria.Bernal |Date reviewed= February 28 , 2026 |Date reviewed= September 7 , 2026 |Arti
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Patient perceptions of artificial intelligence in ophthalmology: a cross-sectional survey study
Background/Aims Patients have largely been excluded from discussions on the use of their health data in developing medical artificial intelligence (AI), despite being directly affected by its integrat
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Ultrasonographic Features of Morning Glory Syndrome and Peripapillary Staphyloma in Children: Associations With Retinal Detachment
To characterize ultrasonographic features of morning glory syndrome (MGS) and peripapillary staphyloma (PS) in children and their associations with retinal detachment (RD).
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GLP-1 Drugs May Provide Some Protection vs. Eye Diseases - Review of Ophthalmology
GLP-1 Drugs May Provide Some Protection vs. Eye Diseases Review of Ophthalmology